Fluorinated cyclohexanes: Synthesis of amine building blocks of the all-cis 2,3,5,6-tetrafluorocyclohexylamine motif

• Tetiana Bykova,
• Nawaf Al-Maharik,
• Alexandra M. Z. Slawin and
• David O'Hagan

Beilstein J. Org. Chem. 2017, 13, 728–733, doi:10.3762/bjoc.13.72

• ; fluorinated cyclohexanes; Introduction The all-cis-2,3,5,6-tetrafluorocyclohexane 1 ring has been introduced recently as a polarized cyclohexane ring and it has been a focus of our research group to elaborate new building blocks that enable the introduction of this motif into organic discovery programmes